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The mesohyl, formerly known as or as , is the gelatinous matrix within a . It fills the space between the external and the internal . The mesohyl resembles a type of connective tissue and contains several such as , as well as and elements. For a long time, it has been largely accepted that sponges lack true tissue, but it is currently debated as to whether mesohyl and layers are tissues.

The mesohyl is composed of the following main elements: , fibronectin-like molecules, , and a minor component, . These form the extracellular matrix which provides the platform for specific cell adhesion as well as for transduction and .

The mesohyl includes a noncellular colloidal with embedded collagen fibers, spicules and various cells, being as such a type of .Brusca, R.C. & Brusca, G.J. (2003). Invertebrates. 2nd ed. Sunderland, Massachusetts: Sinauer Associates, p. 183.


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