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The peritoneum is the forming the lining of the or in and some invertebrates, such as . It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of supported by a thin layer of connective tissue. This peritoneal lining of the cavity supports many of the abdominal organs and serves as a conduit for their , , and .

The abdominal cavity (the space bounded by the , abdominal muscles, diaphragm, and ) is different from the intraperitoneal space (located within the abdominal cavity but wrapped in peritoneum). The structures within the intraperitoneal space are called "intraperitoneal" (e.g., the and ), the structures in the abdominal cavity that are located behind the intraperitoneal space are called "" (e.g., the ), and those structures below the intraperitoneal space are called "subperitoneal" or "infraperitoneal" (e.g., the ).


Structure

Layers
The peritoneum is one continuous sheet, forming two layers and a between them: the peritoneal cavity.

The outer layer, the parietal peritoneum, is attached to the and the .

(2025). 9781609136062
The , the serous membrane covering the male , is derived from the , an outpouching of the parietal peritoneum.

The inner layer, the visceral peritoneum, is wrapped around the visceral organs, located inside the intraperitoneal space for protection. It is thinner than the parietal peritoneum. The is a double layer of visceral peritoneum that attaches to the gastrointestinal tract. There are often blood vessels, nerves, and other structures between these layers. The space between these two layers is technically outside of the peritoneal sac, and thus not in the peritoneal cavity.

The potential space between these two layers is the peritoneal cavity, filled with a small amount (about 50 mL) of slippery that allows the two layers to slide freely over each other.

The right is continuous with the right and left subhepatic spaces. The allows communication between the greater sac and the lesser sac. The peritoneal space in males is closed, while the peritoneal space in females is continuous with the extraperitoneal pelvis through openings of the , the , and the .


Subdivisions
Peritoneal folds are omentums, mesenteries and ; they connect organs to each other or to the abdominal wall.
(2009). 9781437720556, Elsevier Health Sciences.
There are two main regions of the peritoneal cavity, connected by the .
  • The , represented in red in the diagrams above.
  • The , represented in blue. The lesser sac is divided into two "omenta":
    • The (or hepatogastric) is attached to the lesser curvature of the stomach and the .
      (1984). 9780060466565, Harper & Row.
    • The (or gastrocolic) hangs from the greater curvature of the stomach and loops down in front of the before curving back upwards to attach to the transverse colon. In effect it is draped in front of the intestines like an apron and may serve as an insulating or protective layer.

The is the part of the peritoneum through which most abdominal organs are attached to the abdominal wall and supplied with and vessels and nerves.


Omenta
'''Contains '''
right and left gastroepiploic vessels and fat
Short gastric artery, Left gastroepiploic artery
Left inferior phrenic artery
Right gastroepiploic artery
[[Splenic artery]], Tail of pancreas
The right free margin-hepatic artery, portal vein, and bile duct,lymph nodes and the lymph vessels,hepatic plexus of nerve,all enclosed in perivascular fibrous sheath. Along the lesser curvature of the stomach-left and right gastric artery,gastric group of lymph nodes and lyphatics, branches from gastric nerve.

Right and left gastric artery
Hepatic artery proper, hepatic portal vein, [[bile duct]], [[autonomic nerves]]

">
'''Contains '''
Superior mesenteric artery, accompanying veins, autonomic nerve plexuses, lymphatics, 100–200 lymph nodes and connective tissue with fat
[[Middle colic]]
[[Sigmoid arteries]] and superior rectal artery
Appendicular artery


Other ligaments and folds
'''Contains '''
Round ligament of liver, paraumbilical vein
[[Mesovarium]], [[mesosalpinx]], [[mesometrium]]
[[Ovarian artery]]

In addition, in the there are several structures that are usually named not for the peritoneum, but for the areas defined by the peritoneal folds:

Sexes possessing structure
Male only
Female only
Female only
Male and female
Male and female


Classification of abdominal structures
The structures in the abdomen are classified as intraperitoneal, mesoperitoneal, or infraperitoneal depending on whether they are covered with visceral peritoneum and whether they are attached by mesenteries (mensentery, mesocolon).

IntraperitonealInfraperitoneal / Subperitoneal
Stomach, half of the first part of the duodenum [2.2 cm], jejunum, ileum, cecum, appendix, [[transverse colon]], [[sigmoid colon]], rectum (upper 1/3) Rectum (lower 1/3)
Spleen, [[pancreas]] (only tail)
| | Kidneys, , , Urinary bladder,
In women: ovaries Gonadal blood vessels, Uterus, Fallopian Tubes
| || Inferior vena cava, |

Structures that are intraperitoneal are generally mobile, while those that are retroperitoneal are relatively fixed in their location.

Some structures, such as the kidneys, are "primarily retroperitoneal", while others such as the majority of the duodenum, are "secondarily retroperitoneal", meaning that structure developed intraperitoneally but lost its mesentery and thus became retroperitoneal.


Development
The peritoneum develops ultimately from the of the trilaminar embryo. As the mesoderm differentiates, one region known as the lateral plate mesoderm splits to form two layers separated by an intraembryonic coelom. These two layers develop later into the visceral and parietal layers found in all , including the peritoneum.

As an develops, the various abdominal organs grow into the abdominal cavity from structures in the abdominal wall. In this process they become enveloped in a layer of peritoneum. The growing organs "take their blood vessels with them" from the abdominal wall, and these blood vessels become covered by peritoneum, forming a mesentery.

Peritoneal folds develop from the ventral and of the embryo.


Clinical significance

Imaging assessment
CT scan is a fast (15 seconds) and efficient way in visualising the peritoneal spaces. Although ultrasound is good at visualizing peritoneal collections and ascites, without ionising radiation, it does not provide a good overall assessment of all the peritoneal cavities. MRI scan is also increasingly used to visualise peritoneal diseases, but requires long scan time (30 to 45 minutes) and prone to motion artifacts due to respiration and peristalsis and chemical shift artifacts at the bowel-mesentery interface. Those with peritoneal carcinomatosis, acute pancreatitis, and intraabdominal sepsis may not tolerate prolonged MRI scan.


Peritoneal dialysis
In one form of , called peritoneal dialysis, a glucose solution is sent through a tube into the peritoneal cavity. The fluid is left there for a prescribed amount of time to absorb waste products, and then removed through the tube. The reason for this effect is the high number of arteries and veins in the peritoneal cavity. Through the mechanism of , waste products are removed from the blood.


Peritonitis
Peritonitis is the of the peritoneum. It is more commonly associated to infection from a punctured organ of the abdominal cavity. It can also be provoked by the presence of fluids that produce chemical irritation, such as or . Peritonitis causes fever, tenderness, and pain in the abdominal area, which can be localized or diffuse. The treatment involves rehydration, administration of antibiotics, and surgical correction of the underlying cause. Mortality is higher in the elderly and if present for a prolonged time.
(2025). 9780071748896, McGraw-Hill.


Primary peritoneal carcinoma
Primary peritoneal cancer is a cancer of the cells lining the peritoneum.


Etymology
"Peritoneum" is derived from via . In Greek, means "around", while means "to stretch"; thus, "peritoneum" means "stretched over".


Additional images
Image:Gray403.png|Median sagittal section of pelvis, showing the arrangement of fasciæ
Image:Gray1038.png|Horizontal disposition of the peritoneum in the lower part of the abdomen
Image:Gray1125.png|Sagittal section through posterior abdominal wall, showing the relations of the capsule of the kidney
Image:Gray1224.png|Topography of thoracic and abdominal viscera
Image:Gray1039.png|Horizontal disposition of the peritoneum in the upper part of the [[abdomen]]
Image:Cytology of normal mesothelium.jpg|[[Cytology]] of the normal [[mesothelial cell]]s that line the peritoneum, with typical features.Image by Mikael Häggström, MD. Sources for mentioned features:
-
-
Wright's stain
File:Histology of the mesothelial lining of a hernia sac.jpg| of the peritoneal mesothelial lining, and underlying fibrous tissue. H&E stain.


See also


External links
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