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   » » Wiki: Boil
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A boil, also called a furuncle, is a deep , which is an of the . It is most commonly caused by infection by the Staphylococcus aureus, resulting in a painful swollen area on the caused by an accumulation of and dead tissue. Boils are therefore basically pus-filled nodules. Individual boils clustered together are called . Most human infections are caused by coagulase-positive S. aureus strains, notable for the bacteria's ability to produce , an that can clot blood. Almost any can be infected by S. aureus.


Signs and symptoms
Boils are bumpy, red, -filled lumps around a hair follicle that are tender, warm, and painful. They range from pea-sized to golf ball-sized. A yellow or white point at the center of the lump can be seen when the boil is ready to drain or discharge pus. In a severe infection, an individual may experience , swollen , and fatigue. A recurring boil is called chronic furunculosis.
(2025). 9780323024099, Mosby.
Skin infections tend to be recurrent in many patients and often spread to other family members. Systemic factors that lower resistance commonly are detectable, including: , , and hematologic disorders.

Boils may appear on the buttocks or near the anus, the back, the neck, the belly, the chest, the arms or legs, or even in the ear canal. Boils may also appear around the eye, where they are called .


Complications
The most common complications of boils are and or of the , , , , or other organs. Infections may also spread to the bloodstream () and become life-threatening. S. aureus strains first infect the skin and its structures (for example, , ) or invade damaged skin (cuts, abrasions). Sometimes the infections are relatively limited (such as a , boil, furuncle, or carbuncle), but other times they may spread to other skin areas (causing , , or ). Unfortunately, these bacteria can reach the bloodstream () and end up in many different body sites, causing infections (wound infections, abscesses, , , ) that may severely harm or kill the infected person. S. aureus strains also produce and that likely cause or increase the severity of certain diseases. Such diseases include , , toxic shock syndrome, and scalded skin syndrome.


Causes

Bacteria
Naturally the cause is bacteria such as that are present on the skin. Bacterial colonisation begins in the and can cause local and inflammation. caused by the tumbu fly in Africa usually presents with cutaneous furuncles. for furunculosis include carriage in the nostrils, diabetes mellitus, , lymphoproliferative , , and use of immunosuppressive drugs.


Family history
People with recurrent boils are as well more likely to have a positive family history, take antibiotics, and to have been hospitalised, , or diabetic; they are also more likely to have associated skin diseases and multiple lesions.


Other
Other causes include such as from HIV/AIDS, , , or . Poor hygiene and have also been linked. It may occur following antibiotic use due to the development of resistance to the antibiotics used. An associated skin disease favors recurrence. This may be attributed to the persistent colonization of abnormal skin with S. aureus strains, such as is the case in persons with atopic dermatitis. Boils which recur under the arm, breast or in the groin area may be associated with hidradenitis suppurativa (HS).


Diagnosis
Diagnosis is made through clinical evaluation by a physician, which may include culturing of the lesion. Evaluation can further include imaging, such as an ultrasound, to evaluate for formation of an abscess or other complications.


Treatment
A boil may clear up on its own without bursting, but more often it will need to be opened and drained. This will usually happen spontaneously within two weeks. Regular application of a warm moist compress, both before and after a boil opens, can help speed healing. The area must be kept clean, hands washed after touching it, and any dressings disposed of carefully, in order to avoid spreading the bacteria. A doctor may cut open or "lance" a boil to allow it to drain, but squeezing or cutting should not be attempted at home, as this may further spread the infection. therapy may be recommended for large or recurrent boils or those that occur in sensitive areas (such as the groin, breasts, armpits, around or in the nostrils, or in the ear). An antibiotic should not be used for longer than one month, with at least two months (preferably longer) between uses, otherwise it will lose its effectiveness. Mayo Clinic

Furuncles at risk of leading to serious complications should be incised and drained if antibiotics or steroid injections are not effective. These include furuncles that are unusually large, last longer than two weeks, or occur in the middle of the face or near the spine. Fever and chills are signs of and indicate immediate treatment.

Staphylococcus aureus has the ability to acquire antimicrobial resistance easily, making treatment difficult. Knowledge of the antimicrobial resistance of S. aureus is important in the selection of antimicrobials for treatment.


See also
  • Cutaneous condition
  • Nodule (medicine)


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