In biochemistry, an esterase is a class of enzyme that splits into an acid and an alcohol in a chemical reaction with water called hydrolysis (and as such, it is a type of hydrolase).
A wide range of different esterases exist that differ in their substrate specificity, their protein structure, and their biological function.
EC classification/list of enzymes
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EC 3.1.1: Carboxylic ester hydrolases
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EC 3.1.2: Thiolester hydrolases
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EC 3.1.3: Phosphoric monoester hydrolases
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Phosphatase (EC 3.1.3.x), hydrolyses phosphoric acid monoesters into a phosphate ion and an alcohol
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Alkaline phosphatase, removes phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids.
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Phosphodiesterase (PDE), inactivates the second messenger cAMP
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cGMP specific phosphodiesterase type 5, is inhibited by Sildenafil (Viagra)
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Fructose bisphosphatase (3.1.3.11), converts fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis
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EC 3.1.4: Phosphoric diester hydrolases
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EC 3.1.5: Triphosphoric monoester hydrolases
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EC 3.1.6: Sulfuric ester hydrolases (sulfatases)
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EC 3.1.7: Diphosphoric monoester hydrolases
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EC 3.1.8: Phosphoric triester hydrolases
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(deoxyribonucleases and )
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EC 3.1.11: Exodeoxyribonucleases producing 5'-phosphomonoesters
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EC 3.1.13: Exoribonucleases producing 5'-phosphomonoesters
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EC 3.1.14: Exoribonucleases producing 3'-phosphomonoesters
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EC 3.1.15: Exonucleases active with either ribo- or deoxy-
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(deoxyribonucleases and )
See also
External links
