A bone fracture (abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a partial or complete break in the continuity of any bone in the body. In more severe cases, the bone may be broken into several fragments, known as a comminuted fracture.
A bone fracture may be the result of high force Impact force or Stress fracture, or a minimal trauma injury as a result of certain medical conditions that weaken the bones, such as osteoporosis, osteopenia, bone cancer, or osteogenesis imperfecta, where the fracture is then properly termed a pathologic fracture.
Signs and symptoms
Although bone tissue contains no
nociceptors, a bone fracture is painful for several reasons:
[ MedicineNet – Fracture Medical Author: Benjamin C. Wedro, MD, FAAEM.]
Damage to adjacent structures such as nerves, muscles or blood vessels, spinal cord, and nerve roots (for spine fractures), or cranial contents (for skull fractures) may cause other specific signs and symptoms.
Complications
Some fractures may lead to serious complications, including a condition known as compartment syndrome. If not treated, eventually, compartment syndrome may require
amputation of the affected limb. Other complications may include non-union, where the fractured bone fails to heal, or malunion, where the fractured bone heals in a deformed manner. One form of malunion is the malrotation of a bone, which is especially common after femoral and tibial fractures.
Complications of fractures may be classified into three broad groups, depending upon their time of occurrence. These are as follows –
-
Immediate complications – occurs at the time of the fracture.
-
Early complications – occurring in the initial few days after the fracture.
-
Late complications – occurring a long time after the fracture.
|
|
| Systemic
| Systemic
-
Hypovolemic shock
-
ARDS – Acute respiratory distress syndrome
-
Fat embolism syndrome
-
Deep vein thrombosis
-
Pulmonary Embolism syndrome
-
Aseptic traumatic fever
-
Sepsis (in open fracture )
-
Crush syndrome
| Imperfect union of the fracture
|
Local
-
Injury to major vessels
-
Injury to muscles and tendons
-
Injury to joints
-
Injury to viscera
| Local
-
Infection
-
Compartment syndrome
| Others
-
Avascular necrosis
-
Shortening
-
Joint stiffness
-
Sudeck's dystrophy
-
Osteomyelitis
-
Ischaemic contracture
-
Myositis ossificans
-
Osteoarthritis
|
Pathophysiology
The natural process of healing a fracture starts when the injured bone and surrounding tissues bleed, forming a fracture
hematoma. The
clotting to form a blood
clot situated between the broken fragments.
Within a few days,
angiogenesis into the jelly-like matrix of the blood clot. The new blood vessels bring phagocytes to the area, which gradually removes the non-viable material. The blood vessels also bring
in the walls of the vessels and these multiply and produce
collagen fibres. In this way, the blood clot is replaced by a matrix of collagen. Collagen's rubbery consistency allows bone fragments to move only a small amount unless severe or persistent force is applied.
At this stage, some of the fibroblasts begin to lay down bone matrix in the form of collagen monomers. These monomers spontaneously assemble to form the bone matrix, for which bone crystals (calcium hydroxyapatite) are deposited in amongst, in the form of insoluble . This mineralization of the collagen matrix stiffens it and transforms it into bone. In fact, bone is a mineralized collagen matrix; if the mineral is dissolved out of bone, it becomes rubbery. Healing bone callus on average is sufficiently mineralized to show up on X-ray within 6 weeks in adults and less in children. This initial "woven" bone does not have the strong mechanical properties of mature bone. By a process of remodelling, the woven bone is replaced by mature "lamellar" bone. The whole process may take up to 18 months, but in adults, the strength of the healing bone is usually 80% of normal by 3 months after the injury.
Several factors may help or hinder the bone healing process. For example, tobacco smoking hinders the process of bone healing,
Although there are theoretical concerns about NSAIDs slowing the rate of healing, there is not enough evidence to warrant withholding the use of this type analgesic in simple fractures.
Effects of smoking
Smokers generally have lower bone density than non-smokers, so they have a much higher risk of fractures. There is also evidence that smoking delays bone healing.
Diagnosis
A bone fracture may be diagnosed based on the history given and the physical examination performed. Radiographic imaging is often performed to confirm the diagnosis. Under certain circumstances, radiographic examination of the nearby joints is indicated to exclude dislocations and fracture-dislocations. In situations where projectional radiography alone is insufficient, Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) may be indicated.
Classification
In orthopedic
medicine, fractures are classified in various ways. Historically, they are named after the physician who first described the fracture conditions; however, there are more systematic classifications as well.
They may be divided into stable versus unstable depending on the likelihood that they may shift further.
Mechanism
-
Traumatic fracture – a fracture due to sustained trauma. e.g., fractures caused by a fall, road traffic accident, fight, etc.
-
Pathologic fracture – A fracture through a bone that has been made weak by some underlying disease is called a pathological fracture. e.g., a fracture through a bone weakened by metastasis. Osteoporosis is the most common cause of pathological fracture.
-
Periprosthetic fracture – a fracture at the point of mechanical weakness at the end of an implant.
Soft-tissue involvement
-
Closed/simple fractures are those in which the overlying skin is intact
-
Open fracture involve wounds that communicate with the fracture, or where fracture hematoma is exposed, and may thus expose bone to contamination. Open injuries carry a higher risk of infection. Reports indicate an incidence of infection after internal fixation of closed fractures of 1-2%, rising to 30% in open fractures.
-
Clean fracture
-
Contaminated fracture
Displacement
-
Non-displaced
-
Displaced
-
Translated, or ad latus, with sideways displacement.
-
Angulated
-
Rotated
-
Shortened, a reduction in overall bone length when displaced fracture fragments overlap
Fracture pattern
-
Linear fracture – a fracture that is parallel to the bone's long axis
-
Transverse fracture – a fracture that is at a right angle to the bone's long axis
-
Oblique fracture – a fracture that is diagonal to a bone's long axis (more than 30°)
-
Spiral fracture – a fracture where at least one part of the bone has been twisted
-
Compression fracture/wedge fracture – usually occurs in the vertebrae, for example when the front portion of a vertebra in the spine collapses due to osteoporosis (a medical condition which causes bones to become brittle and susceptible to fracture, with or without trauma)
-
Impacted fracture – a fracture caused when bone fragments are driven into each other
-
Avulsion fracture – a fracture where a fragment of bone is separated from the main mass
Fragments
-
Incomplete fracture – a fracture in which the bone fragments are still partially joined; in such cases, there is a crack in the osseous tissue that does not completely traverse the width of the bone.
-
Complete fracture – a fracture in which bone fragments separate completely.
-
Comminuted fracture – a fracture in which the bone has broken into several pieces.
Anatomical location
An anatomical classification may begin with specifying the involved body part, such as the head or arm, followed by more specific localization. Fractures that have additional definition criteria than merely localization often may be classified as subtypes of fractures, such as a Holstein-Lewis fracture being a subtype of a
humerus fracture. Most typical examples in an orthopaedic classification given in the previous section cannot be classified appropriately into any specific part of an anatomical classification, however, as they may apply to multiple anatomical fracture sites.
-
Skull fracture
-
Basilar skull fracture
-
Blowout fracture – a fracture of the walls or floor of the orbit
-
Mandibular fracture
-
Nasal fracture
-
Le Fort fracture of skull – facial fractures involving the maxillary bone and surrounding structures in a usually bilateral and either horizontal, pyramidal, or transverse way.
-
Spinal fracture
-
Cervical fracture
-
Fracture of C1, including Jefferson fracture
-
Fracture of C2, including Hangman's fracture
-
Flexion teardrop fracture – a fracture of the anteroinferior aspect of a cervical vertebral
-
Clay-shoveler fracture – fracture through the spinous process of a vertebra occurring at any of the lower cervical or upper thoracic vertebrae
-
Burst fracture – in which a vertebra breaks from a high-energy axial load
-
Compression fracture – a collapse of a vertebra, often in the form of due to larger compression anteriorly
-
Chance fracture – compression injury to the anterior portion of a vertebral body with concomitant distraction injury to the posterior elements
-
Holdsworth fracture – an unstable fracture dislocation of the thoraco Lumbar vertebrae of the Vertebral column
-
Rib fracture
-
Sternal fracture
-
Shoulder fracture
-
Clavicle fracture
-
Scapular fracture
-
Arm fracture
-
Humerus fracture (fracture of upper arm)
-
Supracondylar fracture
-
Holstein-Lewis fracture – a fracture of the distal third of the humerus resulting in entrapment of the radial nerve
-
Forearm fracture
-
Ulnar fracture
-
Monteggia fracture – a fracture of the proximal third of the ulna with the dislocation of the head of the radius
-
Hume fracture – a fracture of the olecranon with an associated anterior dislocation of the radial head
-
Radius fracture
-
Essex-Lopresti fracture – a fracture of the radial head with concomitant dislocation of the distal radio-ulnar joint with disruption of the interosseous membrane
[ Essex Lopresti fracture at Wheeless' Textbook of Orthopaedics online]
-
Distal radius fracture
-
Galeazzi fracture – a fracture of the radius with dislocation of the distal radioulnar joint
-
Colles' fracture – a distal fracture of the radius with dorsal (posterior) displacement of the wrist and hand
-
Smith's fracture – a distal fracture of the radius with volar (ventral) displacement of the wrist and hand
-
Barton's fracture – an intra-articular fracture of the distal radius with dislocation of the radiocarpal joint
-
Hand fracture
-
Broken finger – a fracture of the carpal phalanges
-
Pelvic fracture
-
Fracture of the hip bone
-
Duverney fracture – an isolated pelvic fracture involving only the iliac wing
-
Femoral fracture
-
Patella fracture
-
Crus fracture
-
Tibia fracture
-
Fibular fracture
-
Maisonneuve fracture – a spiral fracture of the proximal third of the fibula associated with a tear of the distal tibiofibular syndesmosis and the interosseous membrane
-
Le Fort fracture of ankle – a vertical fracture of the antero-medial part of the distal fibula with avulsion of the anterior tibiofibular ligament
-
Bosworth fracture – a fracture with an associated fixed posterior dislocation of the distal fibular fragment that becomes trapped behind the Tibia; the injury is caused by severe external rotation of the ankle
-
Combined tibia and fibula fracture
-
Trimalleolar fracture – involving the lateral malleolus, medial malleolus, and the distal posterior aspect of the tibia
-
Bimalleolar fracture – involving the lateral malleolus and the medial malleolus
-
Pott's fracture
-
Foot fracture
-
Lisfranc fracture – in which one or all of the are displaced from the tarsus
-
Jones fracture – a fracture of the proximal end of the fifth metatarsal
-
March fracture – a fracture of the distal third of one of the metatarsals occurring because of recurrent stress
-
Cuneiform fracture – a fracture of one of the three cuneiform bones typically due to direct blow, axial load, or avulsion
-
Calcaneal fracture – a fracture of the calcaneus (heel bone)
-
Broken toe – a fracture of the pedal phalanges
OTA/AO classification
The Orthopaedic Trauma Association Committee for Coding and Classification published its classification system
in 1996, adopting a similar system to the 1987
AO Foundation system.
In 2007, they extended their system,
unifying the two systems regarding wrist, hand, foot, and ankle fractures.
Classifications named after people
Several classifications are named after the person (
eponymous) who developed it.
-
"Denis classification" for
-
"Frykman classification" for (fractures of radius and ulna)
-
"Gustilo open fracture classification"
-
"Letournel and Judet Classification" for Acetabular fractures
-
"Neer classification" for
-
Seinsheimer classification, Evans-Jensen classification, Pipkin classification, and Garden classification for
Prevention
Both high- and low-force trauma can cause bone fracture injuries.
Preventive efforts to reduce motor vehicle crashes, the most common cause of high-force trauma, include reducing distractions while driving.
Common distractions are driving under the influence and texting or calling while driving, both of which lead to an approximate 6-fold increase in crashes.
Wearing a seatbelt can also reduce the likelihood of injury in a collision.
30 km/h or 20 mph
(as opposed to the more common intracity 50 km/h / 30 mph) also drastically reduce the risk of accident, serious injury and even death in crashes between motor vehicles and humans.
Vision Zero aims to reduce
traffic deaths to zero through better traffic design and other measures and to drastically reduce
traffic injuries, which would prevent many bone fractures.
A common cause of low-force trauma is an at-home fall.
Some sports have a relatively high risk of bone fractures as a common sports injury. Preventive measures depend to some extent on the specific sport, but learning proper technique, wearing protective gear and having a realistic estimation of one's own capabilities and limitations can all help reduce the risk of bone fracture. In contact sports, rules have been put in place to protect athlete health, such as the prohibition of unnecessary roughness in American football.
Taking calcium and vitamin D supplements can help strengthen your bones.
Patterns
|
| 257x257px]] | Linear fracture | Parallel to the bone's long axis | | |
| ]] | Transverse fracture | At a right angle to the bone's long axis | May occur when the bone is bent, | |
| | Oblique fracture | Diagonal to a bone's long axis (more than 30°) | | |
| ]] | Spiral fracture or torsion fracture | At least one part of the bone has been twisted (image shows an Arm wrestling) | Torsion on the bone | May rotate, and must be reduced to heal properly |
| ]] | Compression fracture/wedge fracture | Usually occurs in the vertebrae, for example, when the front portion of a vertebra in the spine collapses due to osteoporosis (a medical condition which causes bones to become brittle and susceptible to fracture, with or without trauma) | | |
| | Impacted fracture | Bone fragments are driven into each other | | |
| ]] | Avulsion fracture | A fragment of bone is separated from the main mass (image shows a Busch fracture) | | |
| ]] | Comminuted fracture | The bone is shattered | often from crushing injuries | |
Treatment
Treatment of bone fractures are broadly classified as surgical or conservative, the latter basically referring to any non-surgical procedure, such as pain management, immobilization or other non-surgical stabilization. A similar classification is
open versus
closed treatment, in which
open treatment refers to any treatment in which the fracture site is opened surgically, regardless of whether the fracture is an open or closed fracture.
Pain management
In arm fractures in children,
ibuprofen is as effective as a combination of
paracetamol and
codeine.
In the EMS setting it might be applicable to administer 1mg/kg of iv
ketamine to achieve a dissociated state.
Immobilization
Since
bone healing is a natural process that will occur most often, fracture treatment aims to ensure the best possible
function of the injured part after healing. Bone fractures typically are treated by restoring the fractured pieces of bone to their natural positions (if necessary), and maintaining those positions while the bone heals. Often, aligning the bone, called reduction, in a good position and verifying the improved alignment with an X-ray is all that is needed. This process is extremely painful without
anaesthesia, about as painful as breaking the bone itself. To this end, a fractured limb usually is immobilized with a
plaster or fibreglass
Orthopedic cast or splint that holds the bones in position and immobilizes the joints above and below the fracture.
When the initial post-fracture oedema or swelling goes down, the fracture may be placed in a removable brace or orthosis. If being treated with surgery, surgical nails, screws, plates, and wires are used to hold the fractured bone together more directly. Alternatively, fractured bones may be treated by the Ilizarov method, which is a form of an external fixator.
Occasionally, smaller bones, such as phalanges of the toes and , may be treated without the cast, by buddy wrapping them, which serves a similar function to making a cast. A device called a Suzuki frame may be used in cases of deep, complex intra-articular digit fractures.
Splinting results in the same outcome as casting in children who have a distal radius fracture with little shifting.
Surgery
Surgery methods of treating fractures have their own risks and benefits, but usually, surgery is performed only if conservative treatment has failed, is very likely to fail, or is likely to result in a poor functional outcome.
With some fractures such as
(usually caused by
osteoporosis), surgery is offered routinely because non-operative treatment results in prolonged immobilisation, which commonly results in complications including chest infections, pressure sores, deconditioning, deep vein thrombosis (DVT), and pulmonary embolism, which are more dangerous than surgery.
When a joint surface is damaged by a
fracture, surgery is also commonly recommended to make an accurate anatomical reduction and restore the smoothness of the joint.
Infection is especially dangerous in bones, due to the recrudescent nature of bone infections. Bone tissue is predominantly extracellular matrix, rather than living cells, and the few blood vessels needed to support this low metabolism are only able to bring a limited number of to an injury to fight infection. For this reason, open fractures and Osteotomy call for very careful antiseptic procedures and prophylactic use of antibiotics.
Occasionally, bone grafting is used to treat a fracture.
Sometimes bones are reinforced with metal.
Bone stimulation
Bone stimulation with either
electromagnetic or
ultrasound waves may be suggested as an alternative to surgery to reduce the healing time for non-union fractures.
The proposed mechanism of action is by stimulating osteoblasts and other proteins that form bones using these modalities. The evidence supporting the use of ultrasound and shockwave therapy for improving unions is very weak
and it is likely that these approaches do not make a clinically significant difference for a delayed union or non-union.
Physical therapy
Physical therapy exercises (either home-based or physiotherapist-led) to improve functional mobility and strength, gait training for hip fractures, and other physical exercises are also often suggested to help recover physical capacities after a fracture has healed.
Children
In children, whose bones are still developing, there are risks of either a growth plate injury or a greenstick fracture.
-
A greenstick fracture occurs due to mechanical failure on the tension side. That is, since the bone is not so brittle as it would be in an adult, it does not completely fracture, but rather exhibits bowing without complete disruption of the bone's cortex in the surface opposite the applied force.
-
Growth plate injuries, as in Salter-Harris fractures, require careful treatment and accurate reduction to make sure that the bone continues to grow normally.
-
Plastic deformation of the bone, in which the bone permanently bends, but does not break, is also possible in children. These injuries may require an osteotomy (bone cut) to realign the bone if it is fixed and cannot be realigned by closed methods.
-
Certain fractures mainly occur in children, including fracture of the clavicle and supracondylar fracture of the humerus.
See also
External links
