Onyalai (Pronunciation: ō′nē-al′ā-ē) is a form of thrombocytopenia that affects some of the population in areas of central Africa.
Signs and symptoms
Onyalai is an acute disease that results in the development of
hematoma on oral
mucous membranes.
Hemorrhagic may develop on the skin, including on the soles of the feet.
The patient does not initially appear to be in distress, which may result in a delay of diagnosis. As the disease progresses,
hematuria and
melena will develop.
Epistaxis,
petechiae and
ecchymoses are common symptoms, as are subconjunctival bleeding and
menorrhagia. On average, bleeding will persist for approximately eight days, and may reoccur.
Approximately 80 percent of cases will exhibit chronic thrombocytopenia. Periodic episodes of acute hemorrhage are also possible and may be severe, possibly leading to shock and
death.
Diagnosis
Treatment
