A tincture is typically an extract of plant or animal material dissolved in ethanol (ethyl alcohol). Solvent concentrations of 25–60% are common, but may run as high as 90%.Groot Handboek Geneeskrachtige Planten by Geert Verhelst In chemistry, a tincture is a solution that has ethanol as the sole solvent. In herbal medicine, alcoholic tinctures are made with various ethanol concentrations, which should be at least 20% alcohol for preservation purposes.
Other solvents for producing tinctures include vinegar, glycerol (also called glycerine), diethyl ether and propylene glycol, not all of which can be used for internal consumption. Ethanol has the advantage of being an excellent solvent for both acidic and basic (alkaline) constituents. A tincture using glycerine is called a glycerite. Glycerine is generally a poorer solvent than ethanol. Vinegar, being acidic, is a better solvent for obtaining alkaloids but a poorer solvent for acidic components. For individuals who choose not to ingest alcohol, non-alcoholic extracts offer an alternative for preparations meant to be taken internally.
Low volatility substances such as iodine and mercurochrome can also be turned into tinctures.
A downside of using alcohol as a solvent is that ethanol has a tendency to denature some organic compounds, reducing or destroying their effectiveness. This tendency can also have undesirable effects when extracting botanical constituents, such as . Certain other constituents, common among them , can become irreversibly denatured, or "pickled" by the alcohol. Alcohol can also have damaging effects on some aromatic compounds.
Ether and propylene glycol based tinctures are not suitable for internal consumption, although they are used in preparations for external use, such as personal care creams and .
Examples of spirits include:
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