Thiolysis is a reaction with a
thiol (R-SH) that cleaves one compound into two.
Thiolysis involves the addition of
coenzyme A to one of the products. This reaction is similar to
hydrolysis, which involves
water instead of a
thiol.
This reaction is seen in
beta-oxidation of
.
The depolymerisation of
with the use of
benzyl mercaptan as nucleophile is also called thiolysis.