Product Code Database
, an example of a 9,10-secosteroid. IUPAC-approved carbon numbering and ring labeling is shown in the picture. Since secosteroids are derived from steroids, they retain the same labeling system as steroids. ]]
A secosteroid () is a type of steroid with a "broken" ring. The word secosteroid derives from the Latin verb secare meaning "to cut", and 'steroid'. Secosteroids are described as a subclass of steroids under the IUPAC nomenclature. (1991). 9780412270604, Chapman & Hall. ISBN 9780412270604 Some sources instead describe them as compounds derived from steroids.
Types or subclasses of secosteroids are defined by the carbon atoms of the parent steroid skeleton where the ring cleavage has taken place. For example, 9,10-secosteroids are derived from bond cleavage between carbon atoms C9 and C10 of the steroid B-ring (similarly 5,6-secosteroids, 13,14-secosteroids, etc.).
The prototypical secosteroid is cholecalciferol (vitamin D3). Its IUPAC systematic is "(5 Z,7 E)-(3 S)- 9,10-secocholestra-5,7,10(19)-trien-3-ol".
Some nonsteroidal estrogens, like doisynolic acid (cleaved on the D ring) and allenolic acid, are also secosteroids or secosteroid-like compounds.
|
|
