Product Code Database
Pyrovalerone ( Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371)US Patent 3314970 is a central nervous system (CNS) stimulant that drug action as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was drug development in the 1980s and had briefly been approved in Spain and France for chronic fatigue or lethargy and as an appetite suppressant, but was withdrawn from both markets around 2001 due to safety concerns including problems with drug abuse and drug dependence. It is closely related on a structural level to a number of other cathinone stimulants, such as α-PVP, MDPV and prolintane.
Side effects of pyrovalerone include decreased appetite, anxiety, fragmented sleep or insomnia, and trembling, Tremor, or . Drug withdrawal symptoms following abuse upon discontinuation often results in depression.
The R-enantiomer of pyrovalerone is devoid of pharmacologic activity.
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