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A promegakaryocyte is a precursor cell for a megakaryocyte, the development of which proceeds as follows:
Promegakaryocytes and other precursor cells to megakaryocytes arise from pluripotential Haematopoiesis progenitors, also known as hemocytoblasts. The megakaryoblast is then produced, followed by the promegakaryocyte, the granular megakaryocyte, and then the mature megakaryocyte. When it is in its promegakaryocyte stage, it is considered an undifferentiated cell.
When the megakaryoblast matures into the promegakaryocyte, it undergoes endoreduplication (2009). 9788131205921, Elsevier India. ISBN 9788131205921 and forms a promegakaryocyte which has Multinucleate, azurophilic granules, and a basophilic cytoplasm. (2002). 9781841842332, CRC Press. ISBN 9781841842332 The promegakaryocyte has rotary motion, but no forward migration.
Megakaryocyte pieces will eventually break off and begin circulating the body as . Platelets are very important because of their role in blood clotting, immune response, and Angiogenesis of new .
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