In human anatomy, the presacral space is inside the pelvis, behind the rectum and in front of the coccyx and sacrum. Normally it is empty, or it contains a pocket of fat.
It is usually covered by sigmoid colon.
Causes of increased pre-sacral space are: ulcerative colitis, granulomatous colitis, lymphogranuloma venereum, and in postirradiation changes, thrombosis of the inferior vena cava and tuberculous proctitis, tumor of the sacrum or posterior wall of the rectum. Carcinomatous deposits in the pelvis can also cause presacral space widening.
Presacral edema is common in patients with heart failure who are confined to bed.
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