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Paralysis (: paralyses; also known as plegia) is a loss of Motor skill function in one or more Skeletal muscle. Paralysis can also be accompanied by a loss of feeling (sensory loss) in the affected area if there is sensory damage. In the United States, roughly 1 in 50 people have been diagnosed with some form of permanent or transient paralysis. The word "paralysis" derives from the Greek language παράλυσις, meaning "disabling of the nerves" on Perseus from παρά ( para) meaning "beside, by" and λύσις ( lysis) meaning "making loose". A paralysis accompanied by involuntary tremors is usually called "palsy".
Pseudoparalysis ( pseudo- meaning "false, not genuine", from Greek ψεῦδος) is voluntary restriction or inhibition of motion because of pain, incoordination, orgasm, or other cause, and is not due to actual muscular paralysis. TheFreeDictionary > pseudoparalysis, in turn citing The American Heritage Medical Dictionary 2007, 2004 In an infant, it may be a symptom of congenital syphilis. Pseudoparalysis can be caused by extreme mental stress and is a common feature of mental disorders such as panic anxiety.
Paralysis can occur in newborns due to a Birth defect defect known as spina bifida. Spina bifida causes one or more of the vertebrae to fail to form vertebral arches within the infant, which allows the spinal cord to protrude from the rest of the spine. In extreme cases, this can cause spinal cord function inferior to the missing vertebral arches to cease. This cessation of spinal cord function can result in paralysis of lower extremities. Documented cases of paralysis of the anal sphincter in newborns have been observed when spina bifida has gone untreated. While life-threatening, many cases of spina bifida can be corrected surgically if operated on within 72 hours of birth.
Ascending paralysis presents in the lower limbs before the upper limbs. It can be associated with:
Ascending paralysis contrasts with descending paralysis, which occurs in conditions such as botulism.
Paralysis can be seen in breeds of dogs that are chondrodysplastic. These dogs have short legs, and may also have short muzzles. Their intervertebral disc material can calcify and become more brittle. In such cases, the disc may rupture, with disc material ending up in the spinal canal, or rupturing more laterally to press on spinal nerves. A minor rupture may only result in paresis, but a major rupture can cause enough damage to cut off circulation. If no signs of pain can be elicited, surgery should be performed within 24 hours of the incident, to remove the disc material and relieve pressure on the spinal cord. After 24 hours, the chance of recovery declines rapidly, since with continued pressure, the spinal cord tissue deteriorates and dies.
Another type of paralysis is caused by a fibrocartilaginous embolism. This is a microscopic piece of disc material that breaks off and becomes lodged in a spinal artery. Nerves served by the artery will die when deprived of blood.
The German Shepherd Dog is especially prone to developing degenerative myelopathy. This is a deterioration of nerves in the spinal cord, starting in the posterior part of the cord. Affected dogs will become incontinent and gradually weaker in the hind legs as nerves die off. Eventually, their hind legs become useless. This disease also affects other large breeds of dogs.
Cats with a heart murmur may develop blood clots that travel through arteries. If a clot is large enough to block one or both femoral arteries, there may be hind leg paralysis because the major source of blood flow to the hind leg is blocked.
Many snakes and trees exhibit powerful neurotoxins that can cause nonpermanent paralysis or death.
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