Minaxolone

 ( General Anesthetics ) 

Minaxolone ( CCI-12923) is a neuroactive steroid which was developed as a general anesthetic but was withdrawn before registration due to toxicity seen with long-term administration in rats, and hence was never marketed.

(1999). 9780702021671, W.B. Saunders. . ISBN 9780702021671

(2025). 9780323037075, Elsevier Health Sciences. ISBN 9780323037075

It is a positive allosteric modulator of the GABAA receptor,

(2025). 9780123668462, Academic Press. ISBN 9780123668462

as well as, less potently, a positive allosteric modulator of the glycine receptor.

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Chemistry

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See also

• Alfadolone
• Alfaxolone
• Ganaxolone
• Hydroxydione
• Pregnanolone
• Renanolone

Categories: General Anesthetics, Neurosteroids, Secondary Alcohols, Ethers, Dimethylamino Compounds, Ketones, Gabaa Receptor Positive Allosteric Modulators, Glycine Receptor Agonists, Pregnanes, Ethoxy Compounds

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