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A micropenis or microphallus is an unusually small . A common criterion is a dorsal (measured on top) penile length of at least 2.5 standard deviations smaller than the human penis size for age. A micropenis is stretched penile length equal to or less than 1.9 (0.75 ) in term , and 9.3 cm (3.67 in) in adults. The condition is usually recognized shortly after . The term is most often used medically when the rest of the penis, , and are without ambiguity, such as . Traditionally, a microphallus describes a micropenis with . Micropenis incidence is about 1.5 in 10,000 male in .ScienceDaily.com (2004). " Surgeons Pinch More Than An Inch From The Arm To Rebuild A Micropenis," 6 Dec. 2004, retrieved 2 April 2012.


Causes
Of the abnormal conditions associated with micropenis, most are conditions of reduced prenatal production or effect, such as abnormal testicular development (testicular dysgenesis), Klinefelter syndrome, Leydig cell hypoplasia, specific defects of or dihydrotestosterone synthesis (17,20-lyase deficiency, 5α-reductase deficiency), androgen insensitivity syndromes, inadequate stimulation ( deficiency), and other forms of congenital . Micropenis can also occur as part of many genetic malformation syndromes that do not involve the sex chromosomes. It is sometimes a sign of congenital growth hormone deficiency or congenital . Several genes affect penis and digit size without detectable hormone abnormalities.

In addition, exposure to some estrogen-based fertility drugs like diethylstilbestrol (DES) has been linked to genital abnormalities or a smaller than normal penis.

After evaluation to detect any of the conditions described above, micropenis can often be treated in infancy with injections of various , such as human chorionic gonadotropin and .


Treatment

Hormone treatment
Growth of the penis both before birth and during childhood and puberty is strongly influenced by and, to a lesser degree, the . However, later endogenous hormones mainly have value in the treatment of micropenis caused by hormone deficiencies, such as or .

Regardless of the cause of micropenis, if it is recognized in infancy, a brief course of testosterone is often prescribed (usually no more than three months). This usually induces a small amount of growth, confirming the likelihood of further growth at puberty, but rarely achieves normal size. No additional testosterone is given during childhood, to avoid unwanted and . There is also some evidence that premature administration of testosterone can lead to reduced penis size in the adult.

Testosterone treatment is resumed in adolescence only for boys with hypogonadism. Penile growth is completed at the end of puberty, similar to the completion of , and provision of extra testosterone to post-pubertal adults produces little or no further growth.


Surgery
Because hormone treatment rarely achieves average size, several surgical techniques similar to for penis enlargement have been devised and performed, but they are not generally considered successful enough to be widely adopted and are rarely performed in childhood.

In extreme cases of micropenis, there is barely any shaft, and the glans appears to sit almost on the pubic skin. From the 1960s until the late 1970s, it was common for sex reassignment and surgery to be recommended. This was especially likely if evidence suggested that response to additional testosterone and pubertal testosterone would be poor. With parental acceptance, the boy would be reassigned and renamed as a girl, and surgery performed to remove the testes and construct an artificial vagina (). This was based on the now-questioned idea that gender identity was shaped entirely from socialization, and that a man with a small penis can find no acceptable place in society.

Johns Hopkins Hospital, the center most known for this approach, performed twelve such reassignments from 1960 to 1980, most notably that of (whose penis was destroyed by a circumcision accident), overseen by . By the mid-1990s, reassignment was less often offered, and all three premises had been challenged. Former subjects of such surgery, vocal about their dissatisfaction with the adult outcome, played a large part in discouraging this practice. Sexual reassignment is rarely performed today for severe micropenis (although the question of raising the boy as a girl is sometimes still discussed).


See also


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