Plants in the genus Humulus and Cannabis produce terpenophenolic metabolites, such as humulone and tetrahydrocannabinol respectively.
The antibiotic marinone produced by marine bacteria is another example.
Terpenophenolics can also be isolated from animals. The terpenophenolics methoxyconidiol, epiconicol and didehydroconicol, isolated from the ascidian Aplidium aff. Aplidium densum, show antiproliferative activity.
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