Isoquercetin

 ( Quercetin Glycosides ) 

Isoquercetin, isoquercitrin or isotrifoliin is a flavonoid, a type of chemical compound. It is the 3- O-glucoside of quercetin. Isoquercitrin can be isolated from various plant species including Mangifera indica (mango) and Rheum nobile (the Noble rhubarb). It is also present in the leaves of Annona squamosa, Camellia sinensis (tea). and Vestia foetidaC. Brevis, M. Quezada, P. Bustamante, L. Carrasco, A. Ruiz, S. Donoso, Huevil (Vestia foetida) poisoning of cattle in Chile The Veterinary record 156(14):452-3 May 2005

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Spectral data The lambda-max for isoquercetin is 254.8 and 352.6 Nanometre.

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Potential clinical uses Isoquercetin is presently being investigated for prevention of thromboembolism in selected cancer patients NCT02195232 and as an anti-fatigue agent in kidney cancer patients treated with sunitinib. NCT02446795

There is a single case report of its use in the successful treatment of prurigo nodularis, a difficult to treat pruritic eruption of the skin.

However it belongs to the PAINS (Pan-assay interference compounds) categories of chemicals.

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See also

• Quercitrin

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