Hematologic diseases are disorders which primarily affect the blood and Blood formation. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease and complications from chemotherapy or transfusions.
Myeloid
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Hemoglobinopathy (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
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(lack of red blood cells or hemoglobin)
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Iron-deficiency anemia
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Megaloblastic anemia
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Vitamin B12 deficiency
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Folate deficiency
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Hemolytic anemias (destruction of red blood cells)
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Genetic disorders of RBC membrane
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Hereditary spherocytosis
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Hereditary elliptocytosis
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Congenital dyserythropoietic anemia
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Genetic disorders of RBC metabolism
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Glucose-6-phosphate dehydrogenase deficiency (G6PD)
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Pyruvate kinase deficiency
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Immune mediated hemolytic anemia (direct Coombs test is positive)
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Autoimmune hemolytic anemia
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Warm antibody autoimmune hemolytic anemia
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Idiopathic
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Systemic lupus erythematosus (SLE)
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Evans syndrome (antiplatelet antibodies and hemolytic antibodies)
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Cold autoimmune hemolytic anemia
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Cold agglutinin disease
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Paroxysmal cold hemoglobinuria (rare)
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Infectious mononucleosis
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Alloimmune hemolytic anemia
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Hemolytic disease of the newborn (HDN)
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Rh disease (Rh D)
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ABO hemolytic disease of the newborn
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Anti-Kell hemolytic disease of the newborn
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Rhesus c hemolytic disease of the newborn
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Rhesus E hemolytic disease of the newborn
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Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
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Drug induced immune mediated hemolytic anemia
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Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
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Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
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Direct physical damage to RBCs
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Microangiopathic hemolytic anemia
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Secondary to artificial heart valve(s)
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Aplastic anemia
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Fanconi anemia
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Diamond–Blackfan anemia (inherited pure red cell aplasia)
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Acquired pure red cell aplasia
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Decreased numbers of cells
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Myeloproliferative disorders (Increased numbers of cells)
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Polycythemia vera (increase in the number of cells in general)
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Polycythemia (increase in the number of red blood cells)
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Leukocytosis (increase in the number of white blood cells)
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Thrombocytosis (increase in the number of platelets)
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Myeloproliferative disorder
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Transient myeloproliferative disease
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Coagulopathy (disorders of bleeding and coagulation)
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Thrombocytosis
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Recurrent thrombosis
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Disseminated intravascular coagulation
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Disorders of clotting proteins
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Hemophilia
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Von Willebrand disease
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Disseminated intravascular coagulation
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Protein S deficiency
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Antiphospholipid syndrome
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Disorders of platelets
Hematological malignancies
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Hematological malignancies
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Hodgkin's disease
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Non-Hodgkin's lymphoma {includes the next five entries}
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Burkitt's lymphoma
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Anaplastic large cell lymphoma
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Splenic marginal zone lymphoma
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Hepatosplenic T-cell lymphoma
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Angioimmunoblastic T-cell lymphoma (AILT)
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increased WBC
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Acute lymphocytic leukemia (ALL)
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Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
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Acute myelogenous leukemia (AML)
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Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia
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Chronic Idiopathic Myelofibrosis (MF)
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Chronic myelogenous leukemia (CML)
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T-cell prolymphocytic leukemia (T-PLL)
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B-cell prolymphocytic leukemia (B-PLL)
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Chronic neutrophilic leukemia (CNL)
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Hairy cell leukemia (HCL)
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T-cell large granular lymphocyte leukemia (T-LGL)
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Aggressive NK-cell leukemia
Miscellaneous
Hematological changes secondary to non-hematological disorders
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