Glucoraphanin

 ( Glucosinolates ) 

Glucoraphanin is a glucosinolate found in broccoli, Mustard plant and other cruciferous vegetables.

Glucoraphanin is converted to sulforaphane by the enzyme myrosinase. In plants, sulforaphane deters insect predators and acts as a selective antibiotic.

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Synthesis Glucoraphanin is derived from dihomomethionine, which is methionine chain-elongated twice. The sulfinyl group is chiral, and has R absolute configuration. The stereochemistry is set when an oxygen atom added to 4-methylthiobutylglucosinolate by a flavonoid monooxygenase.

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Research Sulforaphane and other have been studied for their potential biological effects. The isothiocyanates formed from glucosinolates are under laboratory research to assess the expression and activation of enzymes that metabolism , such as . Observational studies have been conducted to determine if consumption of cruciferous vegetables affects cancer risk in humans, but there is insufficient clinical evidence to indicate that consuming glucoraphanin and other isothiocyanates in cruciferous vegetables is beneficial, according to a 2017 review.

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Plant breeding

of broccoli have been plant breeding to contain two to three times more glucoraphanin than standard broccoli. Romanesco broccoli may contain up to ten times more glucoraphanin than typical broccoli varieties. Frostara, Black Tuscany, and red cabbage also contain higher levels of glucoraphanin than broccoli.

Categories: Glucosinolates, Brassica Oleracea

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