Fenarimol

 ( Aromatase Inhibitors ) 

Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, Apple scab and mildew fungi. It is used on , trees, , tomatoes, peppers, eggplants, cucurbitaceae. It is mainly used to control powdery mildew. It works by inhibiting the fungus's biosynthesis of important steroid molecules (via blockade of the CYP51 enzyme).

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History Fenarimol was developed by Eli Lilly and Company around 1971.

Derivatives of this compound are being researched in an open source manner for possible treatment of eumycetoma.

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Synthesis Fenarimol is made by the reaction of 2,4'-dichlorobenzophenone with an organolithium pyrimidine made via bromine-lithium exchange.

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External links

Categories: Aromatase Inhibitors, 2-chlorophenyl Compounds, Endocrine Disruptors, Fungicides, Nonsteroidal Antiandrogens, Pyrimidines, Xenoestrogens, 4-chlorophenyl Compounds, Tertiary Alcohols

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