Eryptosis ( Erythrocyte apoptosis or Red blood cell programmed death) is a type of apoptosis that occurs in injured (RBCs) because of various factors including hyperosmolarity, oxidative stress, energy depletion, heavy metals exposure or xenobiotics. Like apoptosis, eryptosis is characterized by cell shrinkage, cell membrane blebbing, activation of proteases, and phosphatidylserine exposure at the outer membrane leaflet.
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