Cyclopyrrolones

 ( Chemical Classes Of Psychoactive Drugs ) 

Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.

Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the GABAA receptor of neurotransmitter GABA. The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its enantiopure drug, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include:

• Pagoclone – anxiolytic
• Pazinaclone – anxiolytic
• Suproclone – anxiolytic
• Suriclone – anxiolytic