Buphedrone, also known as α-methylamino-butyrophenone ( MABP), is a stimulant of the phenethylamine and cathinone that was first synthesized in 1928.
Chemistry
Buphedrone is a β-ketone and is related to the naturally occurring compounds
cathinone and
cathine. It is also related to
methamphetamine, differing by the β-
ketone substituent (at the β-carbon) and an
ethyl group replacing the
methyl group at the carbon at the α-position relative to the
amine. Another name for buphedrone is phenylacetoethyl-methylamine.
Buphedrone as free base is very unstable; it is prone to dimerization like other α-amino ketones. Because of this, it is sold as various salts, with a hydrochloride being most common.
Effects
Buphedrone
hyperlocomotion, potentiates the release of
dopamine from
dopaminergic nerve terminals in the
brain, and causes appetite suppression. It also causes a possibly dangerous effect of decreasing subjective feeling of thirst. The effects of buphedrone have also been compared to
methamphetamine, with more euphoria and less physical stimulation. Most commonly reported effects include:
-
Elevated mood, euphoria
-
Increased alertness
-
Dilated (rare)
-
Slurred speech (rare)
-
Increased heart rate
-
Talkativeness
-
Increased empathy and sense of communication
-
Increased sex drive
-
Temporary erectile dysfunction
-
Restlessness
-
Insomnia
-
Increased motivation
Depending on the route of administration, the duration varies from approximately 2.5 (IV) to 6 hours (orally) and may be followed by unpleasant symptoms associated with Drug withdrawal, which may include:
-
Dysphoria
-
Tiredness
-
Sweating
-
Loss of concentration
Legal status
As of October 2015, buphedrone is a controlled substance in China.
Buphedrone is an Anlage II controlled drug in Germany.
In the United States, buphedrone is considered a schedule 1 controlled substance as a positional isomer of mephedrone.
See also
