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Boldo
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Peumus boldus, commonly known as boldo (from the name foḻo), is a of tree in the family and the only species in the Peumus. It is to the central region of , between 33° and 40° southern latitude. Boldo has also been introduced to and , though it is not often seen outside .

Due to its common name, it is often confused with the species Plectranthus ornatus, known as falso boldo ("false boldo"), boldo paraguayo or boldo rastrero, which has led to confusion about the uses, properties and toxicity of both species.


Description
Boldo, together with litre, quillay, , bollén and other indigenous plants, is a characteristic component of the forests endemic to central Chile. Its leaves, which have a strong, woody and slightly bitter flavor and -like aroma, are used for culinary purposes, primarily in Latin America. The leaves are used in a similar manner to and are also prepared as a , primarily in Chile and .

The edible fruits are small about 2 centimeters in diameter, green in color and having a pleasant flavor. Though not well known outside their native range, boldo fruits, which appear between December and February, are very tasty, nutritious, small, green, edible spheres. Boldo's assertive flavor comes primarily from the presence of the chemical , which is also present in the plant.


Uses
In Brazil, Argentina, Chile, Uruguay, and Paraguay, boldo is mixed with or other teas to moderate its flavor. Some families keep a boldo plant at home for this purpose, although boldo are readily available in nearly all supermarkets.

Boldo and plants with similar properties are widely used as mild in various South American countries in both urban and rural areas, even among people who do not usually drink other than . In Brazilian , boldo is an officially listed plant, as a and used for treatment of mild .ANVISA (Agência Nacional de Vigilância Sanitária). 2011 Formulario de Fitoterapicos da Farmacopeia Brasileira . Brasilia, Governo Federal do Brasil.

Boldo is in the family , which is closely related to the family (which includes many other plants used for their aromatic leaves, such as , cassia, , and ).

Boldo leaves have a slightly bitter, soft flavor and a bit of a rough, coniferous taste when brewed in tea. They are used as a culinary herb to spice many savory dishes including fish, mushrooms, and vegetables and as a component in sauces. In some local South American kitchens boldo leaves are also popular for wrapping frying fish and meat. Boldo fruits, when dried, are used to make spicy condiments.P N Ravindran CABI, Dec 28, 2017 The Encyclopedia of Herbs and Spices


Toxicity
In 2009, the European Medicines Agency assessed boldo as follows:

Boldo leaf contains the alkaloid . Boldo leaf also contains 2–4% of volatile oil. Major constituents reported as: (16–38%), 1,8-cineole (11–39%) and (9–29%).Mariano, 2019 Ascaridole is highly toxic, and this raises concerns about the suitability of boldo leaf in traditional herbal medicinal products.

and effects in rats were observed with very high doses (800 mg/kg) of a dry extract of boldine in the first days of pregnancy, not present at lower doses.

Most investigations have been carried out using boldine.

Limited information is available on herbal preparations of boldo leaf and where studies have been reported, details of the preparations are usually lacking. There are no reported genotoxicity or carcinogenicity studies with herbal preparations of boldo leaf.

Boldo oil should not be used internally or externally. Where boldo leaf is used, the total exposure to ascaridole should be considered from a safety standpoint. The levels of ascaridole in herbal medicinal products should be quantified. In view of the low solubility of ascaridole in water, the use of aqueous extracts including herbal teas could be accepted. The use of ethanolic extracts of boldo leaf is not considered acceptable for traditional herbal medicinal products, in view of the potentially higher levels of the toxic ascaridole constituent.


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