Actoxumab is a human Monoclonality antibody designed for the prevention of recurrence of Clostridioides difficile infection.
This drug, along with bezlotoxumab, was developed through Phase II efficacy trials by a partnership between Medarex Inc and MassBiologics of the University of Massachusetts Medical School. The project was then licensed to Merck & Co., Inc. for further development and commercialization.
A study compared it with bezlotoxumab (that targets CD toxin-B) and found Actoxumab less effective. New treatment for C.diff infections reduces recurrences by 40%, study finds
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