Zariadres was an Orontid dynasty ruler of Sophene in the early 2nd century BC. According to Strabo, he was a general of the Seleucid Empire ruler Antiochus III who was made ruler of Sophene, although most scholars believe that he was a member of the Orontid dynasty, which ruled Armenia and Sophene. After the Seleucids were defeated by the Romans in 190 BC, Zariadres and his ally Artaxias I of Greater Armenia (possibly also Zariadres' son) revolted against the Seleucids, became independent kings and expanded their territories. The last information about Zariadres' reign dates to 188 BC. He was succeeded as king by Mithrobouzanes, possibly his son.
the defeat of Antiochus III by the Romans at the Battle of Magnesia in 190 BC, Zariadres and Artaxias I revolted and with Roman consent began to reign as kings under the terms of the Treaty of Apamea in 188 BC—Zariadres over Sophene and Artaxias over Armenia. Zariadres and Artaxias then expanded their kingdoms. Zariadres conquered Acilisene and possibly also Karenitis (around modern-day Erzurum) and Xerxene (likely a scribal corruption of * Derzene, corresponding to Armenian Derjan)․ Another territory mentioned by Strabo, read as either Taronitis (i.e., Taron) or Tamonitis (either Tman or Tmorik), was conquered either by Zariadres or Artaxias. Zariadres may have later recognized the suzerainty of Antiochus IV Epiphanes in order to be allowed to remain as king of Sophene, rechristening the royal city of Carcathiocerta as Epiphaneia in the Seleucid king's honor. The last information about Zariadres' reign comes from 188 BC. He was succeeded by Mithrobouzanes, who may have been his son. Zariadres appears to have sent Mithrobouzanes to the court of Ariarathes IV of Cappadocia, which suggests the existence of an alliance between the two kings. Ariarathes seems to have helped Mithrobouzanes take the throne of Sophene after some succession crisis. Since Ariarathres reigned until 163 BC, Mithrobouzanes' ascent to the throne of Sophene must have occurred before then.
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