Yupanqui is a surname. Notable people with the surname include:
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Amaru Yupanqui, elder brother of Túpac Inca Yupanqui
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Atahualpa Yupanqui (1908–1992), Argentine singer, songwriter, guitarist, and writer
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Cápac Yupanqui, the fifth Sapa Inca of the Kingdom of Cuzco (beginning around CE 1320) and the last of the Hurin dynasty
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Francisco Tito Yupanqui (1550–1616), Roman Catholic sculptor, created a famous statue of the Blessed Virgin Mary in Bolivia
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Gastón Mansilla Yupanqui, (born 1990), student who killed Víctor Ríos Acevedo in 2012 in Lima, Peru
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Lloque Yupanqui, the third Sapa Inca of the Kingdom of Cuzco (beginning around CE 1260) and a member of the Hurin dynasty
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Manco Inca Yupanqui (1516–1544), one of the Incas of Vilcabamba
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Pachacuti Inca Yupanqui, alias Pachakutiq, the ninth Sapa Inca (1438–1471/1472 CE)
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Titu Cusi Yupanqui (1529–1571), son of Manco Inca Yupanqui, became Inca ruler of Vilcabamba
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Túpac Inca Yupanqui the tenth Sapa Inca (1471–93 CE) of the Inca Empire, and fifth of the Hanan dynasty, younger son and successor of Pachacuti Inca Yupanqui
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Luca Yupanqui, musical contributor to the album Sounds of the Unborn
See also
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Club Social y Deportivo Yupanqui, Argentine football (soccer) club
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Tito Yupanqui, Bolivia, town in the La Paz Department, Bolivia
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Tito Yupanqui Municipality, the third municipal section of the Manco Kapac Province in the La Paz Department, Bolivia