Tioconazole

 ( 21-hydroxylase Inhibitors ) 

Tioconazole is an Antifungal drug of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal . Tioconazole, Mayo Clinic They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.

Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

It was patented in 1975 and approved for medical use in 1982.

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Side effects Side effects of vaginal tioconazole may include temporary vaginitis of the vagina. Vaginal swelling or redness, dysuria, headache, abdominal pain, and upper respiratory tract infection have been reported by people using tioconazole. These side effects may be only temporary, and do not normally interfere with the patient's comfort enough to outweigh the result.

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Synthesis Antimycotic imidazole derivative. A displacement reaction between 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol and 2-chloro-3-(chloromethyl)thiophene is performed.

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