Spee

 ( Dutch-language Surnames ) 

• Spee (noble family), a German noble family
• Friedrich Spee (Friedrich Spee von Langenfeld) (1591–1635), German Jesuit and author of Cautio Criminalis
• Degenhard Bertram von Spee (1681–1736)
• Ambrosius Franziskus von Spee (1730-1791)
• Carl-Wilhelm von Spee (1758-1810)
• Maximilian von Spee (1861–1914), German admiral in the Imperial German Navy
• Clarissa von Spee, German art historian
• Bibian Mentel ( née Spee, 1972–2021), Dutch snowboarder
• Gitte Spee (born 1950), Dutch children's books illustrator
• Just Spee (born 1965), President of the Dutch football association (KNVB)
• Nzante Spee (1953–2005), Cameroonian painter

It may also refer to:

• German cruiser Admiral Graf Spee, scuttled outside the port of Montevideo in 1939
• Spee Club, a coed final club at Harvard University
• Spermidine synthase, an enzyme