RSO or R.S.O. may refer to:
Roles and titles
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Range safety officer, a person responsible for the safe use of rocket vehicles
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Radiation Safety Officer, a person responsible for the safe use of radiation and radioactive materials
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Regional Security Officer, a Diplomatic Security Service Special Agent in charge of security at a US embassy
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Regional Security Office, office in a US embassy or consulate for the Diplomatic Security Service
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Riddare av Svärdsorden, Knight of the Order of the Sword
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Reconnaissance systems officer, operator of surveillance systems and equipment on a Lockheed SR-71 Blackbird aircraft
Organisations
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"Radio Symphony Orchestra", used by a number of orchestras:
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Danish National Symphony Orchestra, based in Denmark
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North German Radio Symphony Orchestra, based in Hamburg, Germany
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Stuttgart Radio Symphony Orchestra, based in Stuttgart, Germany
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Bavarian Radio Symphony Orchestra, based in Munich, Germany
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Frankfurt Radio Symphony Orchestra, based in Frankfurt, Germany
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Finnish Radio Symphony Orchestra
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Swedish Radio Symphony Orchestra
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Vienna Radio Symphony Orchestra
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Richardson Symphony Orchestra, based in Richardson, Texas
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Roanoke Symphony Orchestra, based in Roanoke, Virginia
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Rogers Sportsnet Ontario, a television station in Ontario, Canada
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RSO Records, a record label formed by Robert Stigwood in the late 1960s
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Rohingya Solidarity Organisation, a political organization and former insurgent group in Myanmar (Burma)
Military technology
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Raupenschlepper, Ost, a fully tracked World War II German artillery tractor
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Radschlepper Ost, a wheeled World War II German artillery tractor
Other
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Railway Sub Office (1855–1905), a British Royal Mail office which received mail directly from rail transport
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Reactive Search Optimization, problem-solving methods with integrated online machine-learning capabilities
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Revised Statutes of Ontario, the provincial laws of Ontario, Canada
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Registered sex offender, a person listed on a sex offender registry
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Republic of South Ossetia, a partially recognised country in the South Caucasus
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Resident Space Object, any man-made object in Earth orbit no longer used by anyone
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RSO, musical duo consisting of American musician Richie Sambora and Australian musician Orianthi
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Rick Simpson Oil, a form of cannabis concentrate
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Red Star OS, also abbreviated as RSOS, is a North Korean operating system