Retrovirus particles contain two copies of the RNA genome held together by multiple regions of base pairing (strongest pairing at 5’ ends) which is also called 70S complex (dimer of 35S genomes). This gives viruses evolutionary advantages such as the ability to survive extensive damage to their , as at least parts of both genomes are used during the reverse transcription process. It also explains the high rates of genetic recombination in retroviruses. The retroviral genome is coated by a viral nucleocapsid protein that may function like a single stranded binding protein and therefore enhances processivity and facilitates template exchanges. The nucleocapsid first organizes RNA genomes within the virion and then facilitates reverse transcription within the infected cell.
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