Phosphoprotein

 ( Phosphoproteins ) 

A phosphoprotein is a protein that is posttranslationally modified by the attachment of either a single phosphate group, or a complex molecule such as 5'-phospho-DNA, through a phosphate group. The target amino acid is most often serine, threonine, or tyrosine residues (mostly in ), or aspartic acid or histidine residues (mostly in ). Keyword - Phosphoprotein

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Biological function The phosphorylation of proteins is a major regulatory mechanism in cells.

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Clinical significance

Phosphoproteins have been proposed as for breast cancer. Liquid Biopsy Could Get Boost from Phosphoproteins. 2017 Phosphoproteins in extracellular vesicles as candidate markers for breast cancer

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See also

• Protein phosphorylation
• Phosphoserine

Categories: Phosphoproteins

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