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   » » Wiki: Phenuiviridae
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Phenuiviridae
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Phenuiviridae is a family of negative-strand RNA viruses in the order . , , humans, and mosquitoes serve as natural hosts.


Virology

Structure
Members of Phenuiviridae are viruses with helical morphology. Envelope of these viruses are distributed with icosahedral symmetry (T=12).


Genome
Phenuiviridae is a negative-sense single-stranded RNA virus family. Its genome is segmented into three pieces: L segment (encoding RNA-dependent RNA polymerase), M segment, and S segment.

Some members of the family have gene encoding on the S segment (). The M segment includes envelope glycoproteins encoded in a polyprotein that is cleaved by host . Multiple different proteins can be encoded on the M segment due to by the .


Life cycle
RNA transcripts are through , but not . Translation is terminated by a at the end of each RNA transcript.


Taxonomy
The family contains the following genera:


See also
  • Lone star virus

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