The Pazzi were a powerful family in the Republic of Florence. Their main trade during the fifteenth century was banking. In the aftermath of the Pazzi conspiracy in 1478, members of the family were banished from Florence and their property was confiscated; the family name and coat-of-arms were permanently suppressed by order of the Signoria.
The first apparently historical figure in the family is the who was a captain of the Florentine (Guelph) cavalry at the battle of Montaperti on 4 September 1260, and whose hand was treacherously severed by , causing the standard to fall. His son was a Black Guelph and a follower of Charles de Valois.
Andrea di Guglielmo de' Pazzi (1372–1445) was a banker and merchant. In 1429 he commissioned construction of the Pazzi Chapel in the Franciscan church of Santa Croce in Florence. His son Jacopo de' Pazzi became head of the family in 1464.
Guglielmo di Antonio de' Pazzi married Bianca de' Medici, sister of Lorenzo de' Medici, in 1460; , the sixth of their sixteen children, became archbishop of Florence in 1508.
Francesco de' Pazzi was one of the instigators of the Pazzi conspiracy in 1477–78. He, Jacopo de' Pazzi and Jacopo's brother Renato de' Pazzi were executed after the plot failed.
was a [[condottiere]]; he died at the Battle of Ravenna in 1512.
Maria Maddalena de' Pazzi (1566–1607) was a Carmelite nun and Mysticism; she was canonised in 1669.
The Pazzi were banished from Florence, and their lands and property confiscated. Guglielmo de' Pazzi, husband of Lorenzo's sister Bianca, was placed under house arrest, and later forbidden to enter the city; he went to live at Torre a Decima, near Pontassieve. The family name and coat-of-arms were perpetually suppressed by decree of the Signoria. The name was erased from public registers, and all buildings and streets carrying it were renamed. Their shield with its dolphins was obliterated. Anyone named Pazzi had to take a new name; any man married to a Pazzi was barred from public office. Customs and traditions of the family were suppressed, among them the Easter Saturday ritual involving the flint from Jerusalem.
After the overthrow of Piero de' Medici in 1494, members of the Pazzi family were able to return to Florence.
Palazzo Pazzi or Palazzo Pazzi-Quaratesi was the main seat of the family in the "Canto dei Pazzi", at the intersection of and . It was commissioned by Jacopo de' Pazzi, and built circa 1462–1472 to designs by Giuliano da Maiano. Above its traditionally rusticated ground floor of yellow-ochre sandstone, it had a then-novel first and second floor, with delicate designs in the windows influenced by Brunelleschi. The central court is surrounded on three sides by round-headed arcading, with circular bosses in the .
(or Palazzo Pazzi dell'Accademia Colombaria) is a smaller palace in the Borgo degli Albizi, between Palazzo Ramirez de Montalvo and the Palazzo Nonfinito. It houses a section of the Museum of Natural History of Florence, and hosts temporary exhibitions. The façade is attributed to Bartolomeo Ammannati.
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