OTB may refer to:
Arts
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On the Boards, an arts organization in Seattle, Washington
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Out of the Blue (American band), a jazz ensemble
Computing
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One True Brace, a software coding convention for formatting loops, functions, if statements, and blocks
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Orfeo toolbox, an open source library for remote sensing image processing
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OTA Bitmap, an image file specification for mobile phones (*.otb files)
Sports and games
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Off-track betting, sanctioned gambling on horse racing outside a race track
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Over-the-board, in chess, played on a single physical chessboard (as opposed to correspondence or online chess)
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Off the ball, in association football, a player's movement when not in possession of the ball
Other
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Occupied Territories Bill, proposed Irish law to ban trade with Israeli settlements
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Off the boat, a slang phrase for newly arrived immigrants
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Office du Thé du Burundi, a public company that supports the tea industry in Burundi
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OTB Sports, a media company in Ireland
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Overberg Test Range, or Overberg Toetsbaan, a missile test range in South Africa
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Overseas Trust Bank, a defunct bank of Hong Kong
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OTB Group, a holding company for several fashion brands
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The Old Timer's Bulletin, an amateur radio history journal
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