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Nephrosis is any of various forms of kidney disease (nephropathy). In an old and broad word sense of the term, it is any nephropathy, but in current usage the term is usually restricted to a narrower sense of nephropathy without inflammation or neoplasm, in which sense it is distinguished from nephritis, which involves inflammation. It is also defined as any purely degenerative disease of the renal tubules. Nephrosis is characterized by a set of medical sign called the nephrotic syndrome. Nephrosis can be a primary disorder or can be secondary to another disorder. Nephrotic complications of another disorder can coexist with nephritic complications. In other words, nephrosis and nephritis can be pathophysiology contradistinguished, but that does not mean that they cannot occur simultaneously. Types of nephrosis include amyloid nephrosis and osmotic nephrosis.
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