Mipafox is a highly toxic organophosphate insecticide that is an irreversible acetylcholinesterase inhibitor and is resistant to cholinesterase reactivators. It was developed in the 1950s and is now believed to be no longer in use.
Toxicity
There are
of delayed
neurotoxicity and
paralysis due to acute exposure to mipafox.
Synthesis
Phosphoryl chloride is first reacted with
isopropylamine. The resulting product is then reacted with potassium fluoride or ammonium fluoride to produce mipafox.
See also