Maneb (manganese ethylene-bis-dithiocarbamate) is a fungicide and a polymeric complex of manganese with the ethylene bis (dithiocarbamate) anionic ligand.
Health effects
Exposure to maneb can occur when breathed in; it can irritate the
,
nose, and
throat as well as cause
headache,
fatigue, nervousness, dizziness,
and even unconsciousness. Prolonged or long-term exposure may interfere with the function of the
thyroid. Exposure to maneb is also shown to induce a Parkinson's disease like neurotoxicity in mice.
It is still challenged whether maneb, along with
Paraquat, is an environmental risk factor for Parkinson's disease.
In 2022 a review from India stated that "From the studies we can consider that PQ and MB with its combined effects has tremendous contribution towards neurodegeneration in PD."
Production
Manganese(II) ethylenebis(dithiocarbamate) of low ethylenethiourea (ETU) content is prepared by mixing
Dithiocarbamate (dithiocarbamate) with
formaldehyde in aqueous medium then mixing a water-soluble manganese(II) salt to precipitate the maneb. The product can be further formulated with a metal salt and also with
paraformaldehyde. (See External links for the patent citation)
Applications
Maneb, is a broad spectrum
fungicide that is extensively applied against a wide range of fungal pathogens affecting ornamental plants, food and feed crops. It can also be used to create a toxin-based
animal model of Parkinson's disease, usually in primates.
Environmental effects
Regulation
Maneb was included in a
pesticide ban proposed by the Swedish Chemicals Agency
and approved by the European Parliament on January 13, 2009.
See also
External links
