Luciani is an Italian surname. Notable people with the surname include:
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Albino Luciani (1912–1978), Italian pope of the Catholic Church (John Paul I)
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Alessio Luciani (born 1990), Italian footballer
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Antonino Riccardo Luciani (1931–2020), Italian classical composer and conductor
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Clara Luciani (born 1992), French musician
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Dante Luciani (born 1985), Canadian football wide receiver
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Franco Luciani (born 1981), Argentine musician and composer
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Giacomo Luciani, Italian expert on the geopolitics of energy
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Lucila Luciani de Pérez Díaz (1882–1971), Venezuelan historian, musician and feminist
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Luigi Luciani (1842–1919), Italian neuroscientist
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Luigi Luciani (footballer) (born 1996), Italian football player
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Marie-Ange Luciani (born 1979), French film producer
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Nicoletta Luciani (born 1979), Italian professional volleyball player
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Sebastiano Luciani (c. 1485–1547), Italian Renaissance-Mannerist painter, better known as Sebastiano del Piombo