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   » » Wiki: Lithotripsy
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Lithotripsy
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Lithotripsy is a procedure involving the physical destruction of hardened masses like kidney stones, , or .Königsberger R, Feyh J, Goetz A, Kastenbauer E. Endoscopically-controlled electrohydraulic intracorporeal shock wave lithotripsy (EISL) of salivary stones. J Otolaryngol. 1993 Feb;22(1):12-3 which may be done non-invasively. The term is derived from the words meaning "breaking (or pulverizing) stones" ( + tripso).


Uses
Lithotripsy is a sometimes non-invasive procedure used to break up hardened masses like , or .


Contraindications
Commonly cited absolute contraindications to shock wave lithotripsy (SWL) include pregnancy, or use of platelet aggregation inhibitors, , severe untreated , and untreated urinary tract infections.


Techniques
  • Extracorporeal shock wave therapy (lithotripsy)
  • Intracorporeal (endoscopic lithotripsy):
    • Laser lithotripsy: effective for larger stones (>2 cm) with good stone-free and complication rates.
    • Electrohydraulic lithotripsy
    • Mechanical lithotripsy
    • Ultrasonic lithotripsy: safer for small stones (<10 mm)


History
Surgery was the only method to remove stones too large to pass until and in 1832 invented a surgical instrument (the ) to crush stones inside the without having to open the . To remove a calculus, Civiale inserted his instrument through the and bored holes in the stone. Afterwards, he crushed it with the same instrument and aspirated the resulting fragments or let them flow normally with .

Lithotripsy replaced using lithotrites as the most common treatment beginning in the mid 1980s. In extracorporeal shock wave lithotripsy (ESWL), external shockwaves are focused at the stone to pulverize it. methods use a rigid or flexible scope to reach the stone and direct mechanical or light energy at it. Endoscopy can use lasers as well as other modes of energy delivery: ultrasound or electrohydraulics.

ESWL was first used on kidney stones in 1980. It is also applied to gallstones and pancreatic stones. External shockwaves are focused and pulverize the stone which is located by imaging. The first shockwave lithotriptor approved for human use was the Dornier HM3 (human model 3) derived from a device used for testing aerospace parts. Second generation devices used or generators. American Urological Association guidelines consider ESWL a potential primary treatment for stones between 4 mm and 2 cm.

Electrohydraulic lithotripsy is an industrial technique for fragmenting rocks by using electrodes to create shockwaves. It was applied to bile duct stones in 1975. It can damage tissue and is mostly used in biliary tract specialty centers. Pneumatic mechanical devices have been used with endoscopes, commonly for large and hard stones. Pneumatic lithotripsy has also been successfully applied in the treatment of salivary stones during sialendoscopy, offering a minimally invasive alternative for large or impacted calculi while preserving the salivary duct anatomy.

Laser lithotripsy was introduced in the 1980s. Pulsed dye lasers emit 504 nm (-colored) light that is delivered to the stone by optical fibers through a scope. lasers were developed more recently and produce smaller fragments.

Endovascular lithotripsy is an procedure using a balloon internally fitted with an ultrasound generator.Brinton TJ, Ali ZA, Hill JM et al. Feasibility of shockwave coronary intravascular lithotripsy for the treatment of calcified coronary stenoses, Circulation, 2019;139:834-836 It can be used in the reduction of very calcified coronary arteries, with or without the combined usage of .Hill JM, Kereiakes DJ, Shlofmitz RA et al. Intravascular lithotripsy for treatment of severely calcified coronary artery disease, J Am Coll Cardiol, 2020;76: 2635-2646

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