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Ictonychinae is a subfamily of the mammal family Mustelidae found mainly in the Neotropics (three species) and Africa (three species), with one Eurasian member. It includes the , Patagonian weasel, Ictonyx, African striped weasel, and marbled polecat. These genera were formerly included within a paraphyletic definition of the mustelid subfamily Mustelinae.
Most members have a mask-like bar or larger dark marking across their faces; the African representatives of the group are striped. A defense mechanism common to the group is use of a chemical spray similar to (but not necessarily as strong as) that of .
| Ictonychini |
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| Lyncodontini |
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