Hartke is a surname. Notable people with the surname include:
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Charles A. Hartke (1944–2025), American politician
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Gilbert V. Hartke (1907–1986), drama teacher and activist
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Stephen Hartke (born 1952), American classical composer
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Vance Hartke (1919–2003), American politician
Fictional characters
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Eugene Debs Hartke, a character in the Kurt Vonnegut novel Hocus Pocus
