Hamycin

 ( Antifungals ) 

Hamycin is a pair polyene antimycotic described in India. Aggregation behaviour of hamycin and its interaction with membrane sterols It is a heptaene antifungal compound rather similar in chemical structure to amphotericin B except that it has an additional aromatic Functional group bonded to the molecule. When pure, hamycin is a yellow, powdered solid. There are two versions of hamycin with very similar chemical structures: hamycin A and hamycin B.

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Sources Hamycin is obtained from a strain of streptomyces bacteria growing in soil i.e., Streptomyces pimprina. This compound is being produced in India by Hindustan Antibiotics Limited, located at Pimpri, Pune, Maharashtra, India. It is similar to nystatin and it is more water-soluble.

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Uses It is useful as an antifungal antibiotic drug for topical as well as systemic Mycosis.

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