Fcabs are antibodies fragments engineered from the constant region of an antibody (Fc).
Overview
Fcabs can be expressed as soluble
or they can be engineered back into a full IgG. This type of antibodies are therefore able to recognise two different
antigens, one at their
Fab region and a second one at the
Fc region, hence the name of bispecific antibodies. This antibody fragment is part of the modular antibody technology of
F-star.
See also
-
Antibody Fragments
-
Monoclonal antibodies
