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Ephraim Manessah Sykes (born July 17, 1985) is an American actor and singer. Sykes played the role of George Eacker in the original Broadway cast of the musical Hamilton. In 2017, Sykes originated and was nominated for a Tony Award for the role of David Ruffin in the musical Ain't Too Proud, a stage musical based on the life of The Temptations. In 2024, he starred as George Gibbs in the Broadway revival of the American classic Our Town.Henderson, Kathy Our Town’s Ephraim Sykes on Leaping from Dance to Drama and Celebrating the Quiet Diversity of Grover's Corners Broadway.com, October 8, 2024
In December 2016, he played Seaweed J. Stubbs in NBC's live production of Hairspray Live!.
| 2009 | The Little Mermaid | Ensemble | Lunt-Fontanne Theatre, Broadway theatre |
| The Wiz | Ensemble u/s Scarecrow | New York City Center, Off-Broadway | |
| 2009–2010 | Memphis | Ensemble / Be Black Trio u/s Gator | Shubert Theatre, Broadway |
| 2011 | Ensemble | Alliance Theatre | |
| Memphis | Ensemble / Be Black Trio u/s Gator | Shubert Theatre, Broadway | |
| 2011-2012 | Rent | Benjamin Coffin III | New World Stages, Off-Broadway |
| 2012 | Newsies | Mush / Ensemble | Nederlander Theatre, Broadway |
| 2013-2014 | Temptation / Robert Gordy / Contour / Jackson 5 | Lunt-Fontanne Theatre, Broadway | |
| 2015 | Hamilton | George Eacker / Ensemble u/s Hercules Mulligan / James Madison | The Public Theater, Off-Broadway |
| 2015-2016 | Richard Rodgers Theatre, Broadway | ||
| 2017 | Ain't Too Proud | David Ruffin | Berkeley Repertory Theatre |
| 2018 | Kennedy Center | ||
| Ahmanson Theatre | |||
| Princess of Wales Theatre | |||
| 2019-2020 | Imperial Theatre, Broadway | ||
| 2023 | Pal Joey | Joey Evans | New York City Center, Off-Broadway |
| 2024 | Bye Bye Birdie | Conrad Birdie | Kennedy Center Kennedy Center Bye Bye Birdie |
| 2024-2025 | Our Town | George Gibbs | Ethel Barrymore Theatre, Broadway |
| 2025 | Guys and Dolls | Sky Masterson | Ogunquit Playhouse |
| Hello, Dolly! | Cornelius Hackl | Carnegie Hall |
| 2010 | Astaire Awards | Outstanding Male Dancer in a Broadway Show | Memphis | |
| 2012 | Newsies | |||
| 2016 | Outstanding Ensemble in a Broadway Show | Hamilton | ||
| 2019 | Broadway.com Audience Awards | Favorite Breakthrough Performance (Male) | Ain't Too Proud | |
| Drama League Award | Distinguished Performance | |||
| Tony Award | Best Featured Actor in a Musical | |||
| 2020 | Grammy Award | Best Musical Theater Album | ||
| 2025 | Drama League Award | Distinguished Performance | Our Town | |
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