Chrysler D-50, a compact pickup truck marketed by Chrysler in Australia and based on the Mitsubishi Triton
Dodge D50, a similar compact pickup truck marketed by Chrysler in the United States
D50, a CIE Standard Illuminant, a lighting standard used in colorimetry and also in graphic design as a white point
D50, an intravenous sugar solution of 50% dextrose
D50, the ICD-10 code for iron deficiency anemia
D50, the mass-median-diameter in particle-size distribution measurements, considered to be the average particle size by mass
D50 (film), working title for a Tamil-language film
D50 (radiotherapy), the half maximal inhibitory dose, representing the dose of light or ionising radiation that is required for 50% inactivation of a tumor cell population
D50 road (Croatia), a state route
JNR Class D50, a Japanese steam locomotive class
Lancia D50, a Formula One racing car driven by Juan Manuel Fangio to win the 1956 World Driver's Championship
New South Wales D50 class locomotive, an Australian steam locomotive class
