Product Code Database
Chlorpropham or CIPC is a plant growth regulator and herbicide used as a sprout suppressant for grass weeds, alfalfa, lima and snap beans, blueberries, cane fruit, , cranberry, ladino clover, garlic, seed grass, , spinach, , , safflower, , gladioli and woody nursery stock. It is also used to inhibit potato sprouting and for sucker control in tobacco. Chlorpropham is available in emulsifiable concentrate and liquid formulations.
Chlorpropham is approved for use in the United States as a plant regulator and herbicide only on potatoes. The use of CIPC was banned in the EU and UK in 2019 after it was not reauthorised for use due to toxicity concerns, with sales prohibited from January 2020.
Commercial names include Pin Nip, Bud Nip, Taterpex, Preventol, Elbanil, Metoxon, Nexoval, Stickman Pistols, Preweed, Furloe, Stopgerme-S, Sprout Nip, Mirvale, Bygran, ChlorIPC, Spud-Nic, Spud-Nie, Chloro-IFK, Chloro-IPC, Keim-stop, Triherbicide CIPC, OORJA. For herbicide, an EC formulation is used so that it is dissolvable in water for spray in the field.
Regarding the carcinogenic risk, chlorpropham is classified by the EPA as group E (non-carcinogenic). One of its metabolites is 3-chloroaniline.
The acceptable daily intake ranges from 0.03 mg/kg (FAO 2001 (2025). 9789251045473, Food and Agriculture Organization. ISBN 9789251045473) to 0.05 mg/Kg (EPA 1996 and EC 2003).
A study of the stability of chlorpropham in potatoes (estimated concentration of chlorpropham: 1.8 to 7.6 mg/kg at 10 days post-application) revealed that mean concentration of chlorpropham in the tuber decreased spontaneously by 24% and 42% at 28 days and 65 days postapplication respectively. The study also showed that peeling removed 91–98% and washing 33–47%. Residues of chlorpropham were detected in the boiled potatoes, in the boiling water, in the French-fried potatoes and in the frying oil. According to this study, the theoretical dose for a 20 kg infant eating 100g of crude-peeled tuber would be 0.00018 to 0.00342 mg/kg.
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