Amdoparvovirus is a genus of viruses in the family Parvoviridae in the subfamily Parvovirinae. Mustelids (, , and ), skunk, and raccoons serve as natural hosts. There are 11 species in this genus. Diseases associated with this genus include progressive disorder of immune system.
Taxonomy
The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:
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Amdoparvovirus carnivoran1, Aleutian disease
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Amdoparvovirus carnivoran2, Gray fox amdovirus
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Amdoparvovirus carnivoran3, Racoon dog and fox amdoparvovirus
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Amdoparvovirus carnivoran4, Skunk amdoparvovirus
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Amdoparvovirus carnivoran5, Red panda amdoparvovirus
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Amdoparvovirus carnivoran6, Labrador amdoparvovirus 1
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Amdoparvovirus carnivoran7, Red panda amdoparvovirus 2
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Amdoparvovirus carnivoran8, British Columbia amdoparvovirus
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Amdoparvovirus carnivoran9, Aleutian disease
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Amdoparvovirus carnivoran10, Aleutian disease
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Amdoparvovirus chiropteran1, Sabeidhel virus 1
Structure
Viruses in the genus
Amdoparvovirus have non-enveloped protein particles with T=1 icosahedral symmetry.
[ They are around 18 to 26 nm in diameter and contain a single linear single-stranded DNA genome around 4.8 kb in length.]
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediate clathrin-mediated endocytosis. Replication follows the rolling-hairpin model.[ DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus may exit the host cell by vesicular trafficking following nuclear pore export or be released following cell lysis.
Mustelids, skunk, and raccoons serve as the natural host.] Transmission routes are oral and respiratory.
External links