Acupressure is an alternative medicine technique often used in conjunction with acupuncture or reflexology. It is based on the concept of "life energy" (qi), which purportedly flows through "meridians" in the body. There is no scientific evidence for the existence of acupuncture points, meridians, or qi.
Although some medical studies have suggested that acupressure may be effective at helping manage nausea and vomiting, insomnia, low back pain, , and constipation, among other things, such studies have been found to have a high likelihood of bias. There is no reliable evidence for the effectiveness of acupressure.
A 2011 Cochrane review of four trials using acupuncture and nine studies using acupressure to control pain in childbirth concluded that "acupuncture or acupressure may help relieve pain during labour, but more research is needed". Another Cochrane Collaboration review found that massage provided some long-term benefit for low back pain, and stated: "It seems that acupressure or pressure point massage techniques provide more relief than classic (Swedish) massage, although more research is needed to confirm this."
An acupressure wristband that is claimed to relieve the symptoms of motion sickness and other forms of nausea provides pressure to the P6 acupuncture point, a point that has been extensively investigated. The Cochrane Collaboration reviewed the use of P6 for nausea and vomiting, and found it to be effective for reducing post-operative nausea, but not vomiting. The Cochrane review included various means of stimulating P6, including acupuncture, electro-acupuncture, transcutaneous nerve stimulation, laser stimulation, acustimulation device and acupressure; it did not comment on whether one or more forms of stimulation were more effective; it found low-quality evidence supporting stimulation of P6 compared with sham, with 2 out of 59 trials having low risk of bias. EBM reviewer Bandolier said that P6 in two studies showed 52% of patients with control having a success, compared with 75% with P6.
Quackwatch includes acupressure in a list of methods which have no "rational place" as massage therapy and states that practitioners "may also use irrational diagnostic methods to reach diagnoses that do not correspond to scientific concepts of health and disease."
Clinical use of acupressure frequently relies on the conceptual framework of traditional Chinese medicine. There is no physically verifiable anatomical or histological basis for the existence of acupuncture points or meridians. Quoted by Proponents reply that TCM is a prescientific system that continues to have practical relevance. Acupuncturists tend to perceive TCM concepts in functional rather than structural terms (e.g., as being useful in guiding evaluation and care of patients). Trials using placebo have not demonstrated any statistically significant effect but concluded that acupressure is safe to use along with conventional treatment.
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