The Male Role In Pregnancy Loss And Embryo Implantation Failure

 ( Book Product ) 

Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research

• The Male Role In Pregnancy Loss And Embryo Implantation Failure available on July 22 2018 from Indigo for 248.5
  
• ISBN bar code 9783319188805 ξ1 registered July 22 2018
  
• Product category is Book

• Sku # 978331918880
  

Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.

^ The Male Role In Pregnancy Loss And Embryo Implantation Failure Indigo. ISBN 9783319188805 (revised Jul 2018)